Treatment of facial aging with calcium hydroxyapatite - filling and lifting concept

  • Marisa Gonzaga da Cunha Centro Universitário Saúde ABC/Faculdade de Medicina do ABC, FMABC, Santo André, São Paulo, Brasil
  • Ana Lúcia Gonzaga da Cunha Centro Universitário Saúde ABC/Faculdade de Medicina do ABC, FMABC, Santo André, São Paulo, Brasil
  • Meire Gonzaga Centro Universitário Saúde ABC/Faculdade de Medicina do ABC, FMABC, Santo André, São Paulo, Brasil
  • Glaucia Luciano da Veiga Centro Universitário Saúde ABC/Faculdade de Medicina do ABC, FMABC, Santo André, São Paulo, Brasil
  • Beatriz da Costa Aguiar Alves Centro Universitário Saúde ABC/Faculdade de Medicina do ABC, FMABC, Santo André, São Paulo, Brasil
  • Fernando Luiz A. Fonseca Centro Universitário Saúde ABC/Faculdade de Medicina do ABC, FMABC, Santo André, São Paulo, Brasil
  • Carlos A. Machado Filho Centro Universitário Saúde ABC/Faculdade de Medicina do ABC, FMABC, Santo André, São Paulo, Brasil
Keywords: Facial aging, Sagging, Collagen, Fill, Lift, Hydroxyapatite

Abstract

The face is organized in five different layers (skin, muscles, supportive ligaments, fat pads and bones), which are continuous and interconnected with each other from the scalp to the neck. As a result of aging, changes occur in all its tissues and structures, triggering a cascade of effects in the adjacent areas. Actually, the more it is known about the loss of volume, the better it is to establish the target spots for volume replacement, with consequent more natural- and harmonious-looking outcomes. However, the skin is the outer envelope of the face, which, in the natural process of aging, has a lower capacity to completely accommodate any underlying volume loss or displacement. The result is the formation of creases and folds due to skin sagging. To describe the effects of the injection of calcium hydroxyapatite (CaHA) targeting two objectives at the same time: the restoration of volume loss to compensate the changes in the tridimensional structure and the improvement in skin texture caused by the stimulus to collagen synthesis, thus reducing the sagging of soft tissues envelope. Owing to the mechanism of action of CaHA, its application can be done in two differentiated and little invasive ways so that these objectives can be reached simultaneously. This technique can provide safe, natural and long-lasting rejuvenating effects.

DOI: http://dx.doi.org/10.5281/zenodo.3569835

References

1. Donofrio LM. Fat distribution: a morphologic study of the aging face. Dermatol Surg. 2000; 26(12): 1107-1112.

2. Coleman KR, Carruthers J. Combination therapy with botox and fillers: the new rejuvnation paradigm. Dermatol Ther. 2006; 19(3): 177-188.

3. Coleman SR, Grover R. The anatomy of the aging face: volume loss and changes in 3-dimensional topography. Aesthet Surg J. 2006; 26(1S): S4-9.

4. Erol OO, Agaoglu G. Facial rejuvenation with staged injections of cryopreserved fat and tissue cocktail: clinical outcomes in the past 10 years. Aesthet Surg J. 2013; 33(5): 639-653.

5. Fedok FG. Advances in minimally invasive facial rejuvenation. Curr Opin Otolaryngol Head Neck Surg. 2008; 16(4): 359-368.

6. Cotofana S, Fratila AA, Schenck TL, Redka-Swoboda W, Zilinsky I, Pavicic T. The anatomy of the aging face: a review. Facial Plast Surg. 2016; 32(3): 253-260.

7. Fitzgerald R, Bass LM, Goldberg DJ, Graivier MH, Lorenc ZP. Physiochemical characteristics of poly-L-lactic acid (PLLA). Aesthet Surg J. 2018; 38(suppl 1): S13-S17.

8. Kahn DM, Shaw RB. Overview of current thoughts on facial volume and aging. Facial Plast Surg. 2010; 26(5): 350-355.

9. Stuzin JM. MOC-PSSM CME article: face lifting. Plast Reconstr Surg. 2008; 121(1 Suppl): 1-19.

10. Fernandez-Flores A. Regional variations in the histology of the skin. Am J Dermatopathol. 2015; 37(10): 737-754.

11. Dallara JM, Baspeyras M, Bui P, Cartier H, Charavel MH, Dumas L. Calcium hydroxyapatite for jawline rejuvenation: consensus recommendations. J Cosmet Dermatol. 2014; 13(1): 3-14.

12. Alam M, Gladstone H, Kramer EM, Murphy JP Jr, Nouri K, Neuhaus IM, et al. ASDS guidelines of care: injectable fillers. Dermatol Surg. 2008; 34(Suppl 1): S115-148.

13. Alam M, Tung R. Injection technique in neurotoxins and fillers: Indications, products, and outcomes. J Am Acad Dermatol. 2018; 79(3): 423-435.

14. Sudha PN, Rose MH. Beneficial effects of hyaluronic acid. Adv Food Nutr Res. 2014; 72: 137-176.

15. Levy LL, Emer JJ. Complications of minimally invasive cosmetic procedures: prevention and management. J Cutan Aesthet Surg. 2012; 5(2): 121-132.

16. Kruglikov I, Trujillo O, Kristen Q, Isac K, Zorko J, Fam M, et al. The facial adipose tissue: a revision. Facial Plast Surg. 2016; 32(6): 671-682.

17. Yutskovskaya Y, Kogan E, Leshunov E. A randomized, split-face, histomorphologic study comparing a volumetric calcium hydroxyapatite and a hyaluronic acid-based dermal filler. J Drugs Dermatol. 2014; 13(9): 1047-1052.

18. Fitzgerald R, Carqueville J, Yang PT. An approach to structural facial rejuvenation with fillers in women. Int J Womens Dermatol. 2019; 5(1): 52-67.

19. Mehta-Ambalal SR. Neocollagenesis and neoelastinogenesis: from the laboratory to the clinic. J Cutan Aesthet Sur. 2016; 9(3): 145-151.

20. DeLorenzi C. Complications of injectable fillers, part 2: vascular complications. Aesthet Surg J. 2014; 34(4): 584-600.

21. Amselem M. Radiesse(®): a novel rejuvenation treatment for the upper arms. Clin Cosmet Investig Dermatol. 2016; 9: 9-14.

22. Eviatar J, Lo C, Kirszrot J. Radiesse: advanced techniques and applications for a unique and versatile implant. Plast Reconstr Surg. 2015; 136(5 Suppl): 164S-170S.
Published
2019-12-10
How to Cite
da Cunha, M., da Cunha, A., Gonzaga, M., da Veiga, G., Alves, B., Fonseca, F., & Filho, C. (2019). Treatment of facial aging with calcium hydroxyapatite - filling and lifting concept. European Journal of Biological Research, 9(4), 267-275. Retrieved from http://www.journals.tmkarpinski.com/index.php/ejbr/article/view/230
Section
Research Articles