European Journal of Biological Research 2019-07-20T21:59:12+02:00 Joanna Bródka Open Journal Systems <p><strong>ISSN: 2449-8955</strong><br><strong><a title="MNiSW points: 11" href="" target="_blank" rel="noopener">MNiSW points 2016: 11<br></a></strong><strong><a title="ICV: 100.00" href=",p24783440,3.html" target="_blank" rel="noopener">ICV 2017: 100.00</a></strong><br><strong>Acceptance rate: 2016 - 64%, 2017 - 56%</strong><br><strong>Google-based IF (2017): 0.586&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; h-index: 11</strong></p> Traditional, nutraceutical and pharmacological approaches of Tamarindus indica (Imli) 2019-07-20T21:59:12+02:00 Neelam Soni Vinay Kumar Singh <p>Plants have provided a source of inspiration of novel drug compounds, as plant derived medicines have made large contributions to human health and well-being. An estimate of 75-90% of rural population of the world still relies on herbs for their healthcare. Ayurveda, supposed to be the oldest medical system in the world, provides potential leads to find active and therapeutically useful compounds from plants. Epidemiological studies have consistently demonstrated that consumption of plant- derived foods rich in bioactive phytochemicals have a protective effect against different aliments related to human health.&nbsp; <em>Tamarindus indica</em> is having numerous reported activities like antidiabetic, hypolipidemic, hepatoprotective, anti-ulcer, anti-inflammatory, analgesic, antivenom, antimicrobial, antihelmintic and molluscicidal properties. In spite of these medicinal values this plant is also consumed by rural people as vegetable. It also use as flavoring agent to impart flavor to various dishes and beverage. The present comprehensive review is therefore an effort to give detailed information about botanical description, phytochemical, traditional, nutraceutical and pharmacological approaches of <em>Tamarindus indica</em>.</p> <p><strong>DOI: <a href=""></a></strong></p> 2019-07-18T00:00:00+02:00 ##submission.copyrightStatement## Efficacy of octenidine against Pseudomonas aeruginosa strains 2019-07-18T18:12:38+02:00 Tomasz M. Karpiński <p><em>Pseudomonas aeruginosa</em> is a Gram-negative bacterium causing skin and soft tissue infections, complicated urinary tract infections, blood infections, and nosocomial (hospital-acquired) infections. One of the most often used antiseptics in the skin and soft tissue infections is octenidine. The aim of this study was an evaluation of octenidine activity against strains of <em>P. aeruginosa.</em> Additionally, were compared two staining methods (TTC and MTT) for bacterial growth detection. The study involved eight strains of <em>P. aeruginosa</em>. In order to determine the minimum inhibitory concentration (MIC) of octenidine, the microdilution method was used. For bacterial growth detection was used staining method with 2,3,5-triphenyl-tetrazolium chloride (TTC) and with 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT). In the study has been demonstrated the excellent activity of octenidine against all strains of <em>Pseudomonas aeruginosa</em>. For all tested strains, MICs of octenidine were 0.000195% or 0.00039%, what is equivalent to 1.95 µg/ml and 3.9 µg/ml, respectively. In the study, test with MTT for three strains was more sensitive than a test with TTC. Concluding, octenidine is an antiseptic with high efficacy against <em>Pseudomonas aeruginosa </em>strains. Simultaneously, it was stated that a test with MTT is more sensitive than study with TTC.</p> <p><strong>DOI: <a href=""></a></strong></p> 2019-06-18T00:00:00+02:00 ##submission.copyrightStatement##