Achillea millefolium L. subsp. millefolium essential oil’s antifungal effect

  • Sinem Aydın Giresun University, Department of Biology, Faculty of Science and Arts, Giresun, Turkey
  • Emre Sevindik Faculty of Agriculture, Department of Agricultural Biotechnology, Adnan Menderes University, South Campus, Cakmar, Aydin, Turkey
Keywords: Achillea millefolium subsp. millefolium, Essential oil, Antifungal, Turkey

Abstract

This study was carried out with the aim of determining the antifungal effect of the essential oil isolated from Achillea millefolium subsp. millefolium plant against pathogenic fungi. In order to test the antifungal effect of the oil, an analysis was conducted on a total of 4 pathogen fungi which included Candida albicans, Candida tropicalis, Candida parapsilosis and Saccharomyces cerevisiae, and the effect of the essential oil on the growth of these fungi was investigated. The essential oil of A. millefolium ssp. millefolium had varying degrees of effect on the tested fungi. The highest antifungal effect was found against S. cerevisiae; whereas the lowest antifungal effect was found against C. parapsilosis. Nystatin showed a higher activity than the essential oil of A. millefolium subsp. millefolium against the tested fungi. MIC values ​​of the essential oil against the tested fungi ranged from 1.25 μl/ml to 10 μl/ml. The results obtained indicate that essential oil of A. millefolium subsp. millefolium can be used as an alternative to antifungal agents such as amphotericin, ketoconazole, and fluconazole.

DOI: http://dx.doi.org/10.5281/zenodo.1346338

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Published
2018-08-16
How to Cite
(1)
Aydın, S.; Sevindik, E. Achillea Millefolium L. Subsp. Millefolium Essential Oil’s Antifungal Effect. European Journal of Biological Research 2018, 8, 153-156.
Section
Research Articles