Ayurveda and Yoga practices: a synergistic approach for the treatment of Alzheimer’s disease
Keywords:
Neurodegenerative disease, Alzheimer’s disease, Ayurveda, Yoga, Therapeutic approaches
Abstract
Alzheimer’s disease (AD) is an irreversible and progressive neurodegenerative disease which affects about over 30 million people worldwide. There is no suitable treatment for AD nowadays. The current scenario of the research in the field of the search for suitable therapeutic approaches for the treatment of Alzheimer’s disease should be a shift towards the combinatorial approach of Ayurveda and Yoga. This review is mainly focused on to adapt Ayurveda and Yoga approaches for the treatment of Alzheimer’s disease.
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References
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2. Zawia NΗ, Basha MR. Environmental risk factors and the developmental basis for Alzheimer's disease. Rev Neurosci. 2005; 16(4): 325-338.
3. Mishra SK, Singh SK. Alzheimer’s Disease and immune response: a brief overview. J Alzheimers Dis Parkinsonism. 2017, 7: 371.
4. West S, Bhugra P. Emerging drug targets for Aβ and tau in Alzheimer's disease: a systematic review. British J Clin Pharmacol. 2015; 80(2): 221-34.
5. Nishteswar K, Joshi H, Karra RD. Role of indigenous herbs in the management of Alzheimer's disease. Ancient Sci Life. 2014; 34(1): 3.
6. Joy J. The Ayurvedic perspective on the etiopathogenesis of neurodegeneration. J Health Edu Res Dev. 2015; 3: 137.
7. Sharma R, Amin H. Rasayana therapy: Ayurvedic contribution to improve quality of life. World J Pharmacol Res Tech. 2015; 4: 23-33.
8. Sharma R, Kuca K, Nepovimova E, Kabra A, Rao MM, Prajapati PK. Traditional Ayurvedic and herbal remedies for Alzheimer’s disease: from bench to bedside. Expert Rev Neurother. 2019; 19(5): 359-374.
9. Vyas S, Kothari SL, Kachhwaha S. Nootropic medicinal plants: therapeutic alternatives for Alzheimer’s disease. J Herbal Med. 2019; 2019: 100291.
10. Wang J, Tan L, Yu JT. Prevention trials in Alzheimer’s disease: current status and future perspectives. J Alzh Dis. 2016; 50(4): 927-945.
11. Singh SK, Srivastav S, Castellani RJ, Plascencia-Villa G, Perry G. Neuroprotective and antioxidant effect of Ginkgo biloba extract against AD and other neurological disorders. Neurotherapeutics. 2019; 16(3): 666-674.
12. Penumala M, Zinka RB, Shaik JB, Mallepalli SK, Vadde R, Amooru DG. Phytochemical profiling and in vitro screening for anticholinesterase, antioxidant, antiglucosidase and neuroprotective effect of three traditional medicinal plants for Alzheimer’s Disease and diabetes mellitus dual therapy. BMC Complem Altern Med. 2018; 18(1): 77.
13. Chaudhari KS, Tiwari NR, Tiwari RR, Sharma RS. Neurocognitive effect of nootropic drug Brahmi (Bacopa monnieri) in Alzheimer's disease. Ann Neurosci. 2017; 24(2): 111-122.
14. Jadhav RP, Kengar MD, Narule OV, Koli VW, Kumbhar SB. A review on Alzheimer's Disease (AD) and its herbal treatment of Alzheimer's Disease. Asian J Res Pharmac Sci. 2019; 9(2): 112-122.
15. Beg T, Jyoti S, Naz F, Ali F, Ali SK, Reyad AM, Siddique YH. Protective effect of kaempferol on the transgenic Drosophila model of Alzheimer's disease. CNS Neurolog Disord Drug Targets. 2018; 17(6): 421-429.
16. Wang K, Sun W, Zhang L, Guo W, Xu J, Liu S, Zhou Z, Zhang Y. Oleanolic acid ameliorates Aβ25-35 injection-induced memory deficit in Alzheimer's Disease model rats by maintaining synaptic plasticity. CNS Neurolog Disord Drug Targets. 2018; 17(5): 389-399.
17. Cardoso-Lopes EM, Maier JA, Silva MRD, Regasini LO, Simote SY, et al. Alkaloids from stems of Esenbeckia leiocarpa Engl.(Rutaceae) as potential treatment for Alzheimer disease. Molecules. 2010; 15(12): 9205-9213.
18. Jung HA, Min BS, Yokozawa T, Lee JH, Kim YS, Choi JS. Anti-Alzheimer and antioxidant activities of Coptidis rhizoma alkaloids. Biol Pharm Bull. 2009; 32(8): 1433-1438.
19. Chlebek J, Macáková K, Cahlíková L, Kurfürst M, Kuneš J, Opletal L. Acetylcholinesterase and butyrylcholinesterase inhibitory compounds from Corydalis cava (Fumariaceae). Nat Produ Commun. 2011; 6(5): 1934578X1100600507.
20. Novák Z, Chlebek J, Opletal L, Jiroš P, Macáková K, Kuneš J, Cahlíková L. Corylucinine, a new alkaloid from Corydalis cava (Fumariaceae), and its cholinesterase activity. Nat Prod Commun. 2012; 7(7): 1934578X1200700712.
21. Afshari AR, Sadeghnia HR, Mollazadeh H. A review on potential mechanisms of Terminalia chebula in Alzheimer’s disease. Adv Pharmacol Sci. 2016; 2016: 8964849.
22. Ingale SP, Kasture SB. Protective effect of standardized extract of Passiflora incarnata flower in Parkinson’s and Alzheimer’s disease. Ancient Sci Life. 2017; 36(4): 200.
23. Lopa SS, Hasan MK, Ahammed MS, Islam KM, Alam AK, Rahman MAA, et al. Typhonium trilobatum demonstrates both antioxidant and acetylcholinesterase inhibitory activities in vitro. Bangl Pharm J. 2019; 22(1): 92-98.
24. Taslimi P, Köksal E, Gören AC, Bursal E, Aras A, Kılıç Ö, et al. Anti-Alzheimer, antidiabetic and antioxidant potential of Satureja cuneifolia and analysis of its phenolic contents by LC-MS/MS. Arab J Chem. 2020; 13(3): 4528-4537.
25. Uddin MJ, Abdullah-Al-Mamun M, Biswas K, Asaduzzaman M, Rahman MM. Assessment of anticholinesterase activities and antioxidant potentials of Anisomeles indica relevant to the treatment of Alzheimer’s disease. Orient Pharm Exp Med. 2016; 16(2): 113-121.
26. Thakur M, Virk R, Sangha PS, Saxena V. The Effects of turmeric on Alzheimer’s patients. J Food Sci Nutr Res. 2019; 2: 347-353.
27. Dubey T, Chinnathambi S. Brahmi (Bacopa monnieri): An ayurvedic herb against the Alzheimer's disease. Arch Biochem Biophys. 2019; 676: 108153.
28. Hatziagapiou K, Kakouri E, Lambrou GI, Bethanis K, Tarantilis PA. Antioxidant properties of Crocus sativus L. and its constituents and relevance to neurodegenerative diseases; focus on Alzheimer’s and Parkinson’s disease. Curr Neuropharmacol. 2019; 17(4): 377-402.
29. Finley JW, Gao S. A perspective on Crocus sativus L.(Saffron) constituent crocin: a potent water-soluble antioxidant and potential therapy for Alzheimer’s disease. J Agric Food Chem. 2017; 65(5): 1005-1020.
30. Elufioye TO, Chinaka CG, Oyedeji AO. Antioxidant and anticholinesterase activities of Macrosphyra longistyla (DC) Hiern relevant in the management of Alzheimer’s Disease. Antioxidants. 2019; 8(9): 400.
31. Tepe AS, Ozaslan M. Anti-Alzheimer, anti-diabetic, skin-whitening, and antioxidant activities of the essential oil of Cinnamomum zeylanicum. Indust Crops Prod. 2020; 145: 112069.
32. Liou KT, Shen YC, Chen CF, Tsao CM, Tsai SK. The anti-inflammatory effect of honokiol on neutrophils: mechanisms in the inhibition of reactive oxygen species production. Eur J Pharmacol. 2003; 475(1-3): 19-27.
33. Mahboubi M. Melissa officinalis and rosmarinic acid in management of memory functions and Alzheimer disease. Asian Pacif J Trop Biomed. 2019; 9(2): 47.
34. Ravi SK, Ramesh BN, Mundugaru R, Vincent B. Multiple pharmacological activities of Caesalpinia crista against aluminium-induced neurodegeneration in rats: relevance for Alzheimer’s disease. Environ Toxicol Pharmacol. 2018; 58: 202-211.
35. Kleinrichert K, Alappat B. Comparative analysis of antioxidant and anti-amyloidogenic properties of various polyphenol rich phytoceutical extracts. Antioxidants. 2019; 8(1): 13.
36. Sheeja Malar D, Beema Shafreen R, Karutha Pandian S, Pandima Devi K. Cholinesterase inhibitory, anti-amyloidogenic and neuroprotective effect of the medicinal plant Grewia tiliaefolia- An in vitro and in silico study. Pharm Biol. 2017; 55(1): 381-393.
37. Chethana KR, Senol FS, Orhan IE, Anilakumar KR, Keri RS. Cassia tora Linn.: a boon to Alzheimer's disease for its anti-amyloidogenic and cholinergic activities. Phytomedicine. 2017; 33: 43-52.
38. Chowdhury S, Kumar S. Alpha-terpinyl acetate: A natural monoterpenoid from Elettaria cardamomum as multi-target directed ligand in Alzheimer’s disease. J Funct Foods. 2020; 68: 103892.
39. Chethana KR, Sasidhar BS, Naika M, Keri S. Phytochemical composition of Caesalpinia crista extract as potential source for inhibiting cholinesterase and β-amyloid aggregation: significance to Alzheimer's disease. Asian Pac J Trop Biomed. 2018; 8(10): 500.
40. Lee JE, Kim N, Yeo JY, Seo DG, Kim S, Lee JS, et al. Anti-amyloidogenic effects of asarone derivatives from Perilla frutescens leaves against beta-amyloid aggregation and nitric oxide production. Molecules. 2019; 24(23): 4297.
41. Tan MA, Lagamayo MWD, Alejandro GJD, An SSA. Anti-amyloidogenic and cyclooxygenase inhibitory activity of Guettarda speciosa. Molecules. 2019; 24(22): 4112.
42. Joo HB, Kim JM, Park SY. Anti-amyloidogenic constituents from roots of Dryopteris crassirhizoma in Alzheimer's disease cellular model. Planta Med. 2016; 82(S 01): P472.
43. Liu QS, Jiang HL, Wang Y, Wang LL, Zhang JX, He CH, et al. Total flavonoid extract from Dracoephalum moldavica L. attenuates β-amyloid-induced toxicity through anti-amyloidogenesic and neurotrophic pathways. Life Sci. (2018); 193: 214-225.
44. Eze FN, Ingkaninan K, Prapunpoj P. Transthyretin anti-amyloidogenic and fibril disrupting activities of Bacopa monnieri (L.) Wettst (Brahmi) extract. Biomolecules. 2019; 9(12): 845.
45. Kim DJ, Kim MS, Kim S, Hwang KW, Park SY. Anti‐amyloidogenic effects of Perilla frutescens var. acuta on beta‐amyloid aggregation and disaggregation. J Food Biochem. 2017; 41(5): e12393.
46. Dhouafli Z, Ben Jannet H, Mahjoub B, Leri M, Guillard J, Saidani Tounsi M, et al. 1,2,4-trihydroxynaphthalene-2-O-β-D-glucopyranoside: A new powerful antioxidant and inhibitor of Aβ42 aggregation isolated from the leaves of Lawsonia inermis. Nat Prod Res. 2019; 33(10): 1406-1414.
47. Castro-Silva ES, Bello M, Rosales-Hernández MC, Correa-Basurto J, Hernández-Rodríguez M, Villalobos-Acosta D, et al. Fucosterol from Sargassum horridum as an amyloid-beta (Aβ1-42) aggregation inhibitor: in vitro and in silico studies. J Biomol Struct Dyn. 2020; 1-13: doi: 10.1080/07391102.2020.1729863.
48. Al-Snafi AE. A review on Lagerstroemia indica: A potential medicinal plant. IOSR J Pharm. 2019; 9(6): 36-42.
49. Mazouz W, Haouli NEH, Gali L, Vezza T, Bensouici C, Mebrek S, et al. Antioxidant, anti-alzheimer, anti-diabetic, and anti-inflammatory activities of the endemic halophyte Limonium spathulatum (Desf.) kuntze on LPS-stimulated RAW264 macrophages. South Afr J Bot. 2020; 135: 101-108.
50. Shahinozzaman M, Taira N, Ishii T, Halim MA, Hossain MA, Tawata S. Anti-inflammatory, anti-diabetic, and anti-Alzheimer’s effects of prenylated flavonoids from Okinawa propolis: an investigation by experimental and computational studies. Molecules. 2018; 23(10): 2479.
51. Wangchuk P, Sastraruji T, Taweechotipatr M, Keller PA, Pyne SG. Anti-inflammatory, anti-bacterial and anti-acetylcholinesterase activities of two isoquinoline alkaloids - scoulerine and cheilanthifoline. Nat Prod Commun. 2016; 11(12): 1934578X1601101207.
52. Patil DN, Yadav SR, Patil S, Bapat VA, Jadhav JP. Multidimensional studies of Pancratium parvum Dalzell against acetylcholinesterase: a potential enzyme for Alzheimer’s management. J Am Coll Nutr. 2020; 39(7): 601-618.
53. Kamran M, Kousar R, Ullah S, Khan S, Umer MF, Rashid HU, et al. Taxonomic distribution of medicinal plants for Alzheimer’s Disease: a cue to novel drugs. Int J Alzh Dis. 2020; 2020: 7603015.
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Published
2020-12-14
How to Cite
(1)
Mishra, S.; Singh, S. Ayurveda and Yoga Practices: A Synergistic Approach for the Treatment of Alzheimer’s Disease. European Journal of Biological Research 2020, 11, 65-74.
Section
Review Articles
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